To study changes in nutritional status and safety in dialysis patients undergoing peritoneal dialysis after receiving ONCE Dialyze
- Primary outcome: nutritional assessment with body weight measurement, Prealbumin and with Modified Subjective Global Assessment
- Secondary outcome: Safety Assessment by gastrointestinal side effects, mineral levels (Electrolyte level)
This was a pre-post treatment comparative study (open-label) to determine whether ONCE Dialyze was taken as dietary supplement adding one meal for 15 days in 33 peritoneal dialysis patients at Phramongkutklao Hospital and Chaiyaphum Hospital.
-After receiving ONCE Dialyze for 15 days, patients' nutritional intake (energy, protein, carbs, fat, fiber, potassium, calcium, and magnesium) increased considerably
- Patients who took part in the study showed improved nutritional status. After receiving ONCE Dialyze, the modified SGA score reduced from 24.2 % to 18.2 % (6 % reduction), which was consistent with serum pre-albumin levels and significantlt increased patient's body weight.
- Product safety: There was no evidence of hyperkalemia. High blood calcium and phosphate levels were statistically significant, and none of the subjects in the study experienced any side effects. or have been admitted to a hospital, or have died.
Summary of the study
As ONCE Dialyze is given to people on dialysis who have chronic renal disease as dietary supplement with a typical meal, the patient's nutritional intake including energy, protein, carbohydrate, fat, and fiber was increased, and electrolyte was at proper level. Additionally, it improved the malnutrition condition by the modified SGA score. Dietary supplement intake for particular disease is an efficient method to increase nutrition for those on dialysis who have chronic kidney disease.